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As a nearly daily user of TSRE, I noticed the lack of support for double-clicking on routes to load them. I think this would be a useful feature in the future to allow faster loading of routes to edit. Anybody think this is a good idea?

No.
Because you can create a separate TSRE5 installation for each route, in which the route can be loaded directly without selection.

Yeah.
Because not everyone might want to set up a whole 'nother installation to go check something in another route from time to time, but it won't interfere with those who do.
I still occasionally catch myself reflexively double-clicking on the route I want to open. I've thought about setting it to automagically open my WIP route, but sometimes I want to look at another route to reference or check something, and then I'd have to change my settings again.